Laboratory of Cellular and Environmental Physiology

Keywords

Inflammation; Mechanotransduction; Pathways; Meta-Information; In Silico Analysis; Aryl Hydrocarbon Receptor.

In the Laboratory of Cellular and Environmental Physiology, based in via Selmi, 3, in silico research and teaching activities are carried out. In particular, we analyse connections between cellular networks (pathways) for the representation of complex functions. In this context, we edit pathways that need to be updated by checking their formal correctness (format and naming of genes), improving meta-information (corresponding literature), searching for and updating any new connections (biological reactions). In particular, the laboratory carries out analyses and studies of the inflammatory reaction and mechano-transduction and evaluates their connections, with a particular focus on the possible involvement of xenobiotic sensors such as the Aryl hydrocarbon Receptor (AhR). The target of this activity is the construction of integrated maps with xml/sbml language. This research activity is complemented by teaching activities, which provide students with necessary information as support material for their thesis and basics of in silico biology, with particular reference to standards for representing biological pathways.

Laboratory equipment

For these evaluations, laptops and pc are used.

Teaching, training and research activities

The laboratory allows students to carry out their degree internships and theses (B. Sc., M. Sc., Ph.D.) and hosts Italian and foreign Ph.D. students, offering its resources to support:

- Preparation of undergraduate and PhD theses;

- Development of research projects for post-doctoral fellows.